The tegument ofSchistosoma mansoni: a histochemical investigation

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Suppression of mRNAs Encoding Tegument Tetraspanins from Schistosoma mansoni Results in Impaired Tegument Turnover

Schistosomes express a family of integral membrane proteins, called tetraspanins (TSPs), in the outer surface membranes of the tegument. Two of these tetraspanins, Sm-TSP-1 and Sm-TSP-2, confer protection as vaccines in mice, and individuals who are naturally resistant to S. mansoni infection mount a strong IgG response to Sm-TSP-2. To determine their functions in the tegument of S. mansoni we ...

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The schistosomula tegument antigen as a potential candidate for the early serological diagnosis of schistosomiasis mansoni.

If Schistosoma mansoni infection could be detected in its early stages, especially before the egg deposition in the host tissues, the development of severe pathologic lesions could be efficiently prevented. We therefore developed an indirect enzyme-linked immunosorbent assay based on the detection of specific IgG against schistosomula antigens (ELISA-SmTeg). The assay was applied in sera sample...

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ژورنال

عنوان ژورنال: Parasitology

سال: 1976

ISSN: 0031-1820,1469-8161

DOI: 10.1017/s0031182000058510